Prevalence of HPV Infection and High Risk HPV Genotypes (16, 18), among Monogamous and Polygamous Women, In Zabol, Iran
نویسندگان
چکیده
BACKGROUND This study was performed to compare the prevalence of HPV infection and high risk HPV genotypes [16, 18] between monogamous and polygamous women, in Zabol, Iran. METHODS This cross sectional study was conducted in Zabol in 2006 - 2007. Two hundred sixty five married women attending the Gynecology Clinic for Cervical Disease Screening entered to this study. One hundred sixty two cases had monogamous, and 103 had polygamous husbands. HPV PCR samples were obtained from scrape of papsmear specimens. The biotinylated primers MY09/MY11, GP5+/GP6+, were utilized to enable amplification and detection of positive PCR products. Confirmation of HPV-16 and -18 were done by type-specific PCR primers HPV-16/F, HPV-16/R and HPV-18/F, HPV-18/R. RESULTS Prevalence of HPV infection in monogamous and polygamous groups was 29% and 37.9%, respectively. The most HPV infection was found in 15-25 years group. The most prevalence of infection in monogamous group was HPV-18 and HPV-non16, 18 in 15-25 years, and HPV-16 in 26-35 years group. In polygamous group the most prevalent type was HPV-16, 18 in 15-25 years group. The most prevalent HPV-16 was seen in sever inflammation and dysplasia cytology in both groups. CONCLUSION Prevalence of HPV infection in Zabol is high, and in women with polygamous husbands group is slightly more than monogamous. Screening for this infection must be recommended in this region of Iran.
منابع مشابه
The Frequency of High-risk and Low-risk Human Papillomavirus Genotypes in Different Grades of Cervical Lesions in Shiraz, South-west of Iran
Background and Aim: Determination of HPV genotypes in cervical lesions is essential in screening programs and the impact of current HPV vaccines. Therefore, we investigated the frequency of various HPV genotypes among different grades of cervical lesions. Materials and Methods: In total, 101 biopsy samples of different grades of cervical lesions were collected. Extracted DNA was subjected to P...
متن کاملPrevalence of Human Papillomavirus In Women With Abnormal Pap Smear In Boyer Ahmad City
Abstract Background & aim: Human papillomavirus (HPV) is the most common sexually transmitted disease that is major risk factor for the development of precancerous and cancerous cervical lesions. This study was planned to evaluate the prevalence of HPV and its genotypes in women with abnormal Pap smear who referred to shahid Mofateh clininc. Methods: A total of 67 cervical cytology sample inc...
متن کاملThe Prevalence of HPV Genotypes in Iranian Population: An Update
Background & Objective: Human papillomavirus (HPV) is the main cause of genital warts and some anogenital cancers in male and female subjects which is commonly transmitted by sexual contacts. The objective of this cross-sectional study was to examine the prevalence of HPV genotypes in 10,266 Iranian male and female population, according to their age. Meth...
متن کاملPrevalence and Genotype Distribution of Human Papillomavirus in a Population of Iranian Men
Background and purpose: Human papillomavirus (HPV) often infects humans through sexual contact. Men are carriers of the HPV virus and inadvertently transmit the virus to their sexual partners while being asymptomatic. In many countries strategies are focused on controlling the virus in women and the role of men is ignored. The aim of this study was to determine the prevalence of HPV infection a...
متن کاملHuman papillomavirus and breast cancer in Iran: a meta- analysis
Objective(s):This study aims to investigate the relationship between human papillomavirus (HPV) and breast cancer using meta- analysis. Materials and Methods: Relevant studies were identified reviewing the national and international databases. We also increased the search sensitivity by investigating the references as well as interview with research centers and experts. Finally, quality assess...
متن کامل